hrp0086fc7.2 | Gonads & DSD | ESPE2016

Serum Irisin Concentrations in Lean Adolescents with Polycystic Ovary Syndrome

Bacopoulou Flora , Athanasopoulos Nikos , Mantzou Aimilia , Efthymiou Vassiliki , Lambrou George

Background: The myokine irisin, is associated with the metabolic and hormonal dysregulation of polycystic ovary syndrome (PCOS) in adult women. Recent studies have shown that circulating irisin levels increase in adult women with PCOS.Objective and hypotheses: The purpose of this study was to determine serum concentrations of irisin in lean adolescents with PCOS and healthy controls and to evaluate correlations with clinical, sonographic and hormonal par...